Systematic Review and Meta-Analysis Services
A PRISMA 2020 review, from PROSPERO registration to forest plot.
A systematic review answers a focused question by finding, appraising and combining all relevant studies with a pre-set, reproducible method. A meta-analysis adds statistical pooling of their results. Vsolv Research runs the full process with your team: protocol and PROSPERO registration, database searches, dual screening, risk of bias, meta-analysis and a PRISMA 2020 report.
Who it is for
- Postgraduate and PhD students (a review chapter or a publication)
- Faculty and clinicians
- Pharma medical affairs and HEOR teams needing evidence summaries
What you receive
- PICO question and review protocol
- PROSPERO registration support
- Full search strategies for PubMed/MEDLINE, Scopus, Cochrane Library, plus trial registries and grey literature
- De-duplication and dual independent screening log
- PRISMA 2020 flow diagram
- Data extraction sheets
- Risk of bias assessment (RoB 2, ROBINS-I, Newcastle–Ottawa or QUADAS-2, as fits)
- Meta-analysis (random-effects), heterogeneity, subgroup and sensitivity analyses, publication bias
- Forest and funnel plots at 600 dpi
- GRADE summary of findings table
- Methods and results report, plus manuscript development support for the author team
How the work runs
- Question and feasibility: a scoping search to check how many studies exist.
- Protocol and registration.
- Searching and screening.
- Extraction and risk of bias.
- Analysis and GRADE.
- Report and manuscript support.
How fees are decided
Your fee depends on: number of databases · expected number of records and included studies · number of outcomes · type of analysis (network meta-analysis costs more) · translation of non-English papers · your deadline.
You receive a written scope, agreed timeline and quote within 2 working days of your free consultation.
Scope and limits
Your team approves the protocol and all key decisions. Authorship follows ICMJE: our team members are listed only if they meet the criteria and you agree; otherwise our support is acknowledged.
Frequently asked questions
How long does a systematic review take?
It depends mostly on the number of studies found and the analyses needed. A review with meta-analysis usually takes several months, while scoping and rapid reviews take less time. We agree the timeline in your written quote.
Do I need a systematic review or a meta-analysis?
Every meta-analysis sits inside a systematic review. Results are pooled only when studies are similar enough in design, population and outcome. We check this during the feasibility stage and advise you.
Do I need to register on PROSPERO?
For reviews with a health-related outcome, registration is strongly recommended and increasingly expected by journals. It is free and should be done before data extraction starts.
What software do you use?
R (meta and metafor packages), RevMan, Rayyan for screening, and GRADEpro.
Why do you use two reviewers?
Independent screening and extraction by two reviewers reduces errors and bias, and PRISMA and Cochrane methods expect it.
Last reviewed 27 September 2026.